Francis J. Sweeney

Theoretical and Experimental Design of Atypical Kinase Inhibitors:  Application to p38 MAP Kinase

Kim F. McClure, Yuriy A. Abramov, Ellen R. Laird et al. · Journal of Medicinal Chemistry · 2005 · 79 citations · Full text

Atypical Kinase Inhibitors, Drug Target, P38 Kinase +22

Synthesis and biological activity of selective pipecolic acid-based TNF-α converting enzyme (TACE) inhibitors

Michael A. Letavic, Matt Z. Axt, John T. Barberia et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 75 citations · Full text

Biological Activity, Biochemistry, Natural Sciences +7

Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13

Mark C. Noe, Vijayalakshmi Natarajan, Sheri L. Snow et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 44 citations · Full text

Medicinal Chemistry, Medicine, 3,3-Dimethyl-5-hydroxypipecolic Hydroxamate-based Inhibitors +4

Synthesis and biological activity of piperazine-Based dual MMP-13 and TNF-α converting enzyme inhibitors

Michael A. Letavic, John T. Barberia, Thomas J. Carty et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 40 citations · Full text

Biological Activity, Molecular Pharmacology, Medicinal Chemistry +9

Discovery of 3-OH-3-methylpipecolic hydroxamates: Potent orally active inhibitors of aggrecanase and MMP-13

Mark C. Noe, Vijayalakshmi Natarajan, Sheri L. Snow et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 37 citations · Full text

Medicinal Chemistry, 3-Oh-3-methylpipecolic Hydroxamates, Pharmaceutical Science +10