The Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Cascade Activation Is a Key Signalling Pathway Involved in the Regulation of G₁ Phase Progression in Proliferating Hepatocytes

Hélène Talarmin, Claude Rescan, Sandrine Cariou, +6

Molecular and Cellular Biology

Pd 98059Cell ProliferationProliferating HepatocytesCell CycleCellular Physiology +19

Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation

Qingsheng Liu, Alan Chiu, Long‐Hai Wang, +15

Nature Communications

PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival

Alexandre Coutant, Claude Rescan, David Gilot, +3

Hepatology

Cell DeathSignaling PathwayCell RegulationGrowth FactorReceptor Tyrosine Kinase +14

The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates

Violeta Georgieva Tsonkova, Fredrik Wolfhagen Sand, Xenia Asbæk Wolf, +33

Molecular Metabolism

Mechanism in the Sequential Control of Cell Morphology and S Phase Entry by Epidermal Growth Factor Involves Distinct MEK/ERK Activations

Claude Rescan, Alexandre Coutant, Hélène Talarmin, +4

Molecular Biology of the Cell

Pancreatic islet and progenitor cell surface markers with cell sorting potential

Jacob Hald, Thomas Galbo, Claude Rescan, +11

Diabetologia

Pancreatic CancerCell InteractionPancreatic Islet BiologyPancreatic IsletMolecular Sorting +5

A Safe, Fibrosis‐Mitigating, and Scalable Encapsulation Device Supports Long‐Term Function of Insulin‐Producing Cells

Wanjun Liu, James A. Flanders, Long‐Hai Wang, +17

Small

EGF-induced proliferation of adult human pancreatic duct cells is mediated by the MEK/ERK cascade

Claude Rescan, Stéphanie Le Bras, Véronique Lefebvre, +7

Laboratory Investigation

Signal TransductionPancreatic CancerReceptor Tyrosine KinasePathologyEpithelial-mesenchymal Interactions +8

Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo

Signe Horn, Jeannette S. Kirkegaard, Soraya Hoelper, +8

Molecular Endocrinology

An MLCK-dependent window in late G1 controls S phase entry of proliferating rodent hepatocytes via ERK-p70S6K pathway

Anne Bessard, Alexandre Coutant, Claude Rescan, +5

Hepatology