M.M. Kashipathy

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV–infected mice

Athri D. Rathnayake, Jian Zheng, Yunjeong Kim et al. · Science Translational Medicine · 2020 · 294 citations · Full text

The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase

Yousef M. Alhammad, M.M. Kashipathy, Anuradha Roy et al. · Journal of Virology · 2020 · 136 citations · Full text

Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

Chamandi S. Dampalla, Jian Zheng, Krishani Dinali Perera et al. · Proceedings of the National Academy of Sciences · 2021 · 79 citations · Full text

Protease Inhibitors, Virus Protease, 3C-like Protease +15

Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease

Chamandi S. Dampalla, Yunjeong Kim, Naemi P. Bickmeier et al. · Journal of Medicinal Chemistry · 2021 · 57 citations · Full text

Bioorganic Chemistry, Spatial Disposition, Antiviral Drug +17

Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like Protease

Chamandi S. Dampalla, Athri D. Rathnayake, Anushka C. Galasiti Kankanamalage et al. · Journal of Medicinal Chemistry · 2022 · 36 citations · Full text