Athri D. Rathnayake

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV–infected mice

Athri D. Rathnayake, Jian Zheng, Yunjeong Kim et al. · Science Translational Medicine · 2020 · 294 citations · Full text

Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element

Anushka C. Galasiti Kankanamalage, Yunjeong Kim, Vishnu C. Damalanka et al. · European Journal of Medicinal Chemistry · 2018 · 120 citations · Full text

Piperidine Moiety, Natural Sciences, Drug Discovery +8

Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease

Chamandi S. Dampalla, Yunjeong Kim, Naemi P. Bickmeier et al. · Journal of Medicinal Chemistry · 2021 · 57 citations · Full text

Bioorganic Chemistry, Spatial Disposition, Antiviral Drug +17

Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like Protease

Chamandi S. Dampalla, Athri D. Rathnayake, Anushka C. Galasiti Kankanamalage et al. · Journal of Medicinal Chemistry · 2022 · 36 citations · Full text

Protease inhibitors broadly effective against feline, ferret and mink coronaviruses

Krishani Dinali Perera, Anushka C. Galasiti Kankanamalage, Athri D. Rathnayake et al. · Antiviral Research · 2018 · 35 citations

Protease Inhibitors, Medicine, Viral Pathogenesis +7