Neuroblastoma Arginase Activity Creates an Immunosuppressive Microenvironment That Impairs Autologous and Engineered Immunity

Francis Mussai, Sharon A. Egan, Stuart Hunter, +11

Cancer Research

T-regulatory CellImmunologyPathologyImmunologic MechanismImmunosuppressive Microenvironment +16

Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer

Yeon-Jin Kwon, Kevin Petrie, Boris A. Leibovitch, +18

Molecular Cancer Therapeutics

Peptide SciencePharmacotherapyCancer BiologyTamoxifen SensitivityTumor Biology +20

Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma

Evon Poon, Tong Liang, Yann Jamin, +40

Journal of Clinical Investigation

A Colorectal Cancer 3D Bioprinting Workflow as a Platform for Disease Modeling and Chemotherapeutic Screening

Yordan Sbirkov, Diana Molander, Clément Milet, +7

Frontiers in Bioengineering and Biotechnology

Autistic spectrum disorder (ASD) – Gene, molecular and pathway signatures linking systemic inflammation, mitochondrial dysfunction, transsynaptic signalling, and neurodevelopment

Maria Gevezova, Yordan Sbirkov, Victoria Sarafian, +3

Brain Behavior & Immunity - Health

The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML

Melanie Kahl, Annamaria Brioli, Martin Bens, +17

Leukemia

Non-apl AmlSignal TransductionBiochemistryNatural SciencesMechanism Of Action +1

Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer

Nidhi Bansal, Kevin Petrie, Rossitza Christova, +15

Oncotarget

Sin3a-pf1 InteractionCancer BiologyTumor BiologyTranscriptional RegulationSignaling Pathway +18

Retinoic acid receptor γ is a therapeutically targetable driver of growth and survival in prostate cancer

Kevin Petrie, Zuzanna Urban‐Wójciuk, Yordan Sbirkov, +3

Cancer Reports

Suppression of <scp>MYC</scp> by <scp>PI3K</scp>/<scp>AKT</scp>/<scp>mTOR</scp> pathway inhibition in combination with all‐trans retinoic acid treatment for therapeutic gain in acute myeloid leukaemia

Sven Stengel, Kevin Petrie, Yordan Sbirkov, +9

British Journal of Haematology

World’s First Long-Term Colorectal Cancer Model by 3D Bioprinting as a Mechanism for Screening Oncolytic Viruses

Colin McGuckin, Nico Forraz, Clément Milet, +9

Cancers

EngineeringBiological MicroenvironmentsPathologyBiomedical EngineeringTumor Biology +16