Ryukou Tokuyama

Structure-Activity Relationship (SAR) Studies on Oxazolidinone Antibacterial Agents. 2. Relationship between Lipophilicity and Antibacterial Activity in 5-Thiocarbonyl Oxazolidinones.

Ryukou Tokuyama, Y. Takahashi, Yayoi Tomita et al. · Chemical and Pharmaceutical Bulletin · 2001 · 45 citations · Full text

5-Thiocarbonyl Oxazolidinones, Bioorganic Chemistry, Antibacterial Activity +18

Structure-Activity Relationship (SAR) Studies on Oxazolidinone Antibacterial Agents. 1. Conversion of 5-Substituent on Oxazolidinone.

Ryukou Tokuyama, Y. Takahashi, Yayoi Tomita et al. · Chemical and Pharmaceutical Bulletin · 2001 · 30 citations · Full text

Medicinal Chemistry, Antimicrobial Drug Discovery, Pharmaceutical Science +15

Structure-Activity Relationship (SAR) Studies on Oxazolidinone Antibacterial Agents. 3. Synthesis and Evaluation of 5-Thiocarbamate Oxazolidinones.

Ryukou Tokuyama, Y. Takahashi, Yayoi Tomita et al. · Chemical and Pharmaceutical Bulletin · 2001 · 28 citations · Full text

Hit-to-lead optimization of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of KDR kinase inhibitors

Jürgen Dinges, Irini Akritopoulou‐Zanze, Lee D. Arnold et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 22 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Drug Target +10

Discovery, optimization, and evaluation of non-bile acid FXR/TGR5 dual agonists

Sachiho Miyata, Yuji Kawashima, Miku Sakai et al. · Scientific Reports · 2021 · 15 citations · Full text

Pharmaceutical Science, Biochemistry, Functional Selectivity +13