Annalisa Savardi

Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome

Bruno Pinto, Giovanni Morelli, Mohit Rastogi et al. · Neuron · 2020 · 137 citations · Full text

Down Syndrome, Inflammation, Ds Mice +12

Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain Disorders

Annalisa Savardi, Marco Borgogno, Roberto Narducci et al. · Chem · 2020 · 59 citations · Full text

Design, Synthesis, <i>In Vitro</i> and <i>In Vivo</i> Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome

Marco Borgogno, Annalisa Savardi, Jacopo Manigrasso et al. · Journal of Medicinal Chemistry · 2021 · 20 citations · Full text

APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development

Alessandra Piccini, Enrico Castroflorio, Pierluigi Valente et al. · Cell Reports · 2017 · 17 citations · Full text

Early IGF-1 receptor inhibition in mice mimics preterm human brain disorders and reveals a therapeutic target

Alberto Potenzieri, Sarà Uccella, Deborah Preiti et al. · Science Advances · 2024 · 15 citations · Full text