Simon Kleeb

FimH Antagonists for the Oral Treatment of Urinary Tract Infections: From Design and Synthesis to in Vitro and in Vivo Evaluation

Tobias Klein, Daniela Abgottspon, Matthias Wittwer et al. · Journal of Medicinal Chemistry · 2010 · 197 citations · Full text

Antiadhesion Therapy for Urinary Tract Infections—A Balanced PK/PD Profile Proved To Be Key for Success

Xiaohua Jiang, Daniela Abgottspon, Simon Kleeb et al. · Journal of Medicinal Chemistry · 2012 · 106 citations

Microbial Pathogens, Antibiotic Adjuvant, Antimicrobial Chemotherapy +25

FimH Antagonists: Bioisosteres To Improve the in Vitro and in Vivo PK/PD Profile

Simon Kleeb, Lijuan Pang, Katharina Mayer et al. · Journal of Medicinal Chemistry · 2015 · 93 citations

Vivo Pk/pd Profile, Engineering, Antibiotic Adjuvant +23

Design, synthesis and biological evaluation of mannosyl triazoles as FimH antagonists

Oliver Schwardt, Said Rabbani, Margrit Hartmann et al. · Bioorganic & Medicinal Chemistry · 2011 · 80 citations · Full text

Medicinal Chemistry, Engineering, Medicine +9

FimH Antagonists: Structure–Activity and Structure–Property Relationships for Biphenyl α‐<scp>D</scp>‐Mannopyranosides

Lijuan Pang, Simon Kleeb, Katrin Lemme et al. · ChemMedChem · 2012 · 60 citations

Bioorganic Chemistry, Peptide Science, Antimicrobial Chemotherapy +17