Venkateshwar Mutyam

Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression

Bijoyita Roy, Westley J. Friesen, Yuki Tomizawa et al. · Proceedings of the National Academy of Sciences · 2016 · 223 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Synthetic Aminoglycosides Efficiently Suppress Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations and Are Enhanced by Ivacaftor

Xiaojiao Xue, Venkateshwar Mutyam, Liping Tang et al. · American Journal of Respiratory Cell and Molecular Biology · 2013 · 150 citations · Full text

Medicine, Molecular Biology, Pharmacology +7

A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion

Jyoti Sharma, Ming Du, Eric C. Wong et al. · Nature Communications · 2021 · 125 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Identification of the amino acids inserted during suppression of CFTR nonsense mutations and determination of their functional consequences

Xiaojiao Xue, Venkateshwar Mutyam, Amita Thakerar et al. · Human Molecular Genetics · 2017 · 95 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations

Venkateshwar Mutyam, Ming Du, Xiaojiao Xue et al. · American Journal of Respiratory and Critical Care Medicine · 2016 · 85 citations · Full text

Medicine, Molecular Biology, Pharmacology +14