Subhashree Francis

PAINS in the Assay: Chemical Mechanisms of Assay Interference and Promiscuous Enzymatic Inhibition Observed during a Sulfhydryl-Scavenging HTS

Jayme L. Dahlin, J. Willem M. Nissink, Jessica M. Strasser et al. · Journal of Medicinal Chemistry · 2015 · 341 citations · Full text

Lead Compounds, Chemical Mechanisms, Drug Target +23

Synthesis and Evaluation of Eight- and Four-Membered Iminosugar Analogues as Inhibitors of Testicular Ceramide-Specific Glucosyltransferase, Testicular β-Glucosidase 2, and Other Glycosidases

Jae Chul Lee, Subhashree Francis, Dinah Dutta et al. · The Journal of Organic Chemistry · 2012 · 37 citations

Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins

Christian A. Hassig, Fu‐Yue Zeng, Paul Kung et al. · SLAS DISCOVERY · 2014 · 28 citations · Full text

A Cell-Free Fluorometric High-Throughput Screen for Inhibitors of Rtt109-Catalyzed Histone Acetylation

Jayme L. Dahlin, Rondedrick Sinville, Jonathan Solberg et al. · PLoS ONE · 2013 · 22 citations · Full text

Fungal Cell Biology, Kat Inhibitors, Molecular Biology +17

Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR

Jayme L. Dahlin, J. Willem M. Nissink, Subhashree Francis et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 17 citations · Full text