Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease

Constanze Depp, Ting Sun, Andrew Octavian Sasmita, +27

Nature

Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis

Stefan A. Berghoff, Lena Spieth, Ting Sun, +25

Nature Neuroscience

InflammationNeuroregenerationMedicineBrain-immune InteractionNeuroprotection +8

Molecular Imaging of Fibroblast Activity After Myocardial Infarction Using a ⁶⁸Ga-Labeled Fibroblast Activation Protein Inhibitor, FAPI-04

Zohreh Varasteh, Sarajo K. Mohanta, Stephanie Robu, +11

Journal of Nuclear Medicine

Neuroimmune cardiovascular interfaces control atherosclerosis

Sarajo K. Mohanta, Li Peng, Yuanfang Li, +39

Nature

InflammationVascular DiseaseAutoimmune DiseaseCardiovascular DiseaseMedicine +6

Effects of prebiotics on immunologic indicators and intestinal microbiota structure in perioperative colorectal cancer patients

Xiaoliang Xie, Yaqin He, Hai Li, +10

Nutrition

The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay

Olaf Jahn, Sophie B. Siems, Kathrin Kusch, +6

Frontiers in Cellular Neuroscience

Neurochemical BiomarkersProteomic TechnologyMyelin ProteinsExperimental NeuropathologyAbundant Myelin Constituents +20

Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice

Andrew Octavian Sasmita, Constanze Depp, T. I. Nazarenko, +32

Nature Neuroscience

Root parasitic plant Orobanche aegyptiaca and shoot parasitic plant Cuscuta australis obtained Brassicaceae-specific strictosidine synthase-like genes by horizontal gene transfer

Dale Zhang, Jinfeng Qi, Jipei Yue, +10

BMC Plant Biology

Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease

Erik Schäffner, Mar Bosch-Queralt, Julia M. Edgar, +24

Nature Neuroscience

Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice

Stefan A. Berghoff, Lena Spieth, Ting Sun, +17

Cell Reports