Siddharth Mehra

Combined MEK and STAT3 Inhibition Uncovers Stromal Plasticity by Enriching for Cancer-Associated Fibroblasts With Mesenchymal Stem Cell-Like Features to Overcome Immunotherapy Resistance in Pancreatic Cancer

Jashodeep Datta, Xizi Dai, Anna Bianchi et al. · Gastroenterology · 2022 · 163 citations · Full text

Medicine, Cell Biology, Oncology +17

Cell-Autonomous Cxcl1 Sustains Tolerogenic Circuitries and Stromal Inflammation via Neutrophil-Derived TNF in Pancreatic Cancer

Anna Bianchi, Iago De Castro Silva, Nilesh Deshpande et al. · Cancer Discovery · 2023 · 128 citations · Full text

Medicine, Immunology, Oncology +17

Interactions between Oxidative Stress, Lipid Profile and Antioxidants in Breast Cancer: A Case Control Study

Rakesh Kumar Gupta, Amit Patel, Seema Chugh et al. · Asian Pacific Journal of Cancer Prevention · 2012 · 91 citations · Full text

Medicine, Biochemistry, Oncology +14

Targeting Tumor–Stromal IL6/STAT3 Signaling through IL1 Receptor Inhibition in Pancreatic Cancer

Austin R. Dosch, Samara P. Singh, Xizi Dai et al. · Molecular Cancer Therapeutics · 2021 · 54 citations · Full text

Medicine, Cancer Biology, Oncology +17

Combined Src/EGFR Inhibition Targets STAT3 Signaling and Induces Stromal Remodeling to Improve Survival in Pancreatic Cancer

Austin R. Dosch, Xizi Dai, Michelle L. Reyzer et al. · Molecular Cancer Research · 2020 · 49 citations · Full text

Medicine, Oncology, Pharmacology +17