Roger F. Castilho

Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

Gustav Mattiasson, Mehrdad Shamloo, Gunilla Gidö et al. · Nature Medicine · 2003 · 513 citations

Traumatic Brain Injury, Cell Death, Cerebral Vascular Regulation +16

A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities

Juliana A. Ronchi, Tiago R. Figueira, Felipe Gustavo Ravagnani et al. · Free Radical Biology and Medicine · 2013 · 273 citations

Opening of the mitochondrial permeability transition pore by uncoupling or inorganic phosphate in the presence of Ca²⁺ is dependent on mitochondrial‐generated reactive oxygen species

Alicia J. Kowaltowski, Roger F. Castilho, Anı́bal E. Vercesi · FEBS Letters · 1996 · 246 citations

Permeabilization of the inner mitochondrial membrane by Ca2+ ions is stimulated by t-butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondria

Roger F. Castilho, Alicia J. Kowaltowski, AndréR. Meinicke et al. · Free Radical Biology and Medicine · 1995 · 244 citations

T-butyl Hydroperoxide, Biochemistry, Mitochondrial Function +10

Transgenic mice expressing a Huntington’s disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity

Oskar Hansson, Åsa Petersén, Marcel Leist et al. · Proceedings of the National Academy of Sciences · 1999 · 229 citations