Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance

Antonina V. Kurtova, Kumudha Balakrishnan, Rong Chen, +13

Blood

High expression of lipoprotein lipase in poor risk B-cell chronic lymphocytic leukemia

Daniel Heintel, Dirk Kienle, Medhat Shehata, +14

Leukemia

Lipoprotein LipaseHematological MalignancyHigh ExpressionImmunologyPathology +5

Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia

Rainer Hubmann, Josef D. Schwarzmeier, Medhat Shehata, +4

Blood

PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas

Daniela Laimer, Helmut Dolznig, Karoline Kollmann, +35

Nature Medicine

Lymphoid NeoplasiaMedicinePdgfr BlockadeImmunologyPathology +11

Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia

Medhat Shehata, Susanne Schnabl, Dita Demirtas, +11

Blood

Evaluation of ZAP‐70 expression by flow cytometry in chronic lymphocytic leukemia: A multicentric international harmonization process

Rémi Letestu, Andy C. Rawstron, Paolo Ghia, +20

Cytometry Part B Clinical Cytometry

Deregulated expression of fat and muscle genes in B-cell chronic lymphocytic leukemia with high lipoprotein lipase expression

Martin Bilban, Daniel Heintel, Theresa Scharl, +13

Leukemia

HematologyImmunologyPathologyLipoprotein MetabolismAdult T-cell Leukemia-lymphoma +6

TGF-β1 induces bone marrow reticulin fibrosis in hairy cell leukemia

Medhat Shehata, Josef D. Schwarzmeier, Martin Hilgarth, +3

Journal of Clinical Investigation

Effect of combined spa-exercise therapy on circulating TGF-β1 levels in patients with ankylosing spondylitis

Medhat Shehata, Josef D. Schwarzmeier, Martin Hilgarth, +6

Wiener klinische Wochenschrift

RheumatologyKinesiologySpondyloarthritisExercise PhysiologyExercise Rehabilitation +9

Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2

Markus Duechler, Medhat Shehata, Josef D. Schwarzmeier, +2

Leukemia

Hematological MalignancyProteasome InhibitorsCell RegulationB-cll CellsApoptosis +8