CRISPR/Cas9 delivery with one single adenoviral vector devoid of all viral genes

Eric Ehrke‐Schulz, Maren Schiwon, Theo Leitner, +4

Scientific Reports

One-Vector System for Multiplexed CRISPR/Cas9 against Hepatitis B Virus cccDNA Utilizing High-Capacity Adenoviral Vectors

Maren Schiwon, Eric Ehrke‐Schulz, Andreas Oswald, +4

Molecular Therapy — Nucleic Acids

An Engineered Virus Library as a Resource for the Spectrum-wide Exploration of Virus and Vector Diversity

Wenli Zhang, Jun Fu, Jing Liu, +17

Cell Reports

Viral ReplicationEngineeringSynthetic VirologyMolecular BiologyViral Evolution +20

Viral Vector-Based Delivery of CRISPR/Cas9 and Donor DNA for Homology-Directed Repair in an In Vitro Model for Canine Hemophilia B

Jian Gao, Thorsten Bergmann, Wenli Zhang, +3

Molecular Therapy — Nucleic Acids

Adenoviral Vectors Armed with PAPILLOMAVIRUs Oncogene Specific CRISPR/Cas9 Kill Human-Papillomavirus-Induced Cervical Cancer Cells

Eric Ehrke‐Schulz, Sonja Heinemann, Lukas Schulte, +2

Cancers

ImmunologyCrispr/cas9 SystemTumor BiologyHpv-type-specific Crispr/cas9Cancer-associated Virus +14

A Human In Vitro Model to Study Adenoviral Receptors and Virus Cell Interactions

Raphael L. Tsoukas, Wolfram Volkwein, Jian Gao, +8

Cells

ImmunologyPathologyCrispr/cas9 SystemCancer-associated VirusAntiviral Drug Development +14

Cloning and Large-Scale Production of High-Capacity Adenoviral Vectors Based on the Human Adenovirus Type 5

Eric Ehrke‐Schulz, Wenli Zhang, Maren Schiwon, +6

Journal of Visualized Experiments

Cloning Vector SystemViral ReplicationEngineeringSynthetic VirologyImmunology +15

Cloning and Large-Scale Production of High-Capacity Adenoviral Vectors Based on the Human Adenovirus Type 5

Eric Ehrke‐Schulz, Wenli Zhang, Maren Schiwon, +6

Journal of Visualized Experiments

Designer nuclease‐mediated gene correction via homology‐directed repair in an <i>in vitro</i> model of canine hemophilia B

Thorsten Bergmann, Eric Ehrke‐Schulz, Jian Gao, +5

The Journal of Gene Medicine

Quantification of designer nuclease induced mutation rates: a direct comparison of different methods

Eric Ehrke‐Schulz, Thorsten Bergmann, Maren Schiwon, +4

Molecular Therapy — Methods & Clinical Development

Direct ComparisonGeneticsMolecular BiologyDisease Gene IdentificationDifferent Methods +15