Adrienne M. Wang

A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging

Mark A. McCormick, Joe R. Delaney, Mitsuhiro Tsuchiya et al. · Cell Metabolism · 2015 · 264 citations · Full text

Biology, Replicative Lifespan, Lifespan Extension +15

Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation

Adrienne M. Wang, Yoshinari Miyata, Susan Klinedinst et al. · Nature Chemical Biology · 2012 · 184 citations · Full text

Polyglutamine Protein Degradation, Molecular Neuroscience, Medicine +7

Macroautophagy Is Regulated by the UPR–Mediator CHOP and Accentuates the Phenotype of SBMA Mice

Zhigang Yu, Adrienne M. Wang, Hiroaki Adachi et al. · PLoS Genetics · 2011 · 94 citations · Full text

Androgen Receptor, Mitophagy, Autophagy Activation +21

Inhibition of Hsp70 by Methylene Blue Affects Signaling Protein Function and Ubiquitination and Modulates Polyglutamine Protein Degradation

Adrienne M. Wang, Yoshihiro Morishima, Kelly M. Clapp et al. · Journal of Biological Chemistry · 2010 · 90 citations · Full text

Protein Function, Signal Transduction, Biochemistry +14

A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer

Jonathon L. Burman, Leslie S. Itsara, Ernst‐Bernhard Kayser et al. · Disease Models & Mechanisms · 2014 · 71 citations · Full text