Jayan T. Joseph

3,5-Diaryl-2-aminopyridines as a Novel Class of Orally Active Antimalarials Demonstrating Single Dose Cure in Mice and Clinical Candidate Potential

Yassir Younis, Frédèric Douelle, Tzu‐Shean Feng et al. · Journal of Medicinal Chemistry · 2012 · 134 citations · Full text

Structure–Activity-Relationship Studies around the 2-Amino Group and Pyridine Core of Antimalarial 3,5-Diarylaminopyridines Lead to a Novel Series of Pyrazine Analogues with Oral in Vivo Activity

Yassir Younis, Frédèric Douelle, Diego González Cabrera et al. · Journal of Medicinal Chemistry · 2013 · 49 citations · Full text

Pyridine Core, Antiparasitic Agent, Malaria +17

The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to <i>Plasmodium falciparum</i> parasite resistance

James M. Murithi, Cécile Pascal, Jade Bath et al. · Science Translational Medicine · 2021 · 49 citations · Full text

Structure–Activity Relationship Studies of Orally Active Antimalarial 3,5-Substituted 2-Aminopyridines

Diego González Cabrera, Frédèric Douelle, Yassir Younis et al. · Journal of Medicinal Chemistry · 2012 · 38 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Earlier Frontrunner Compounds +14

Room Temperature Carbonylation of (Hetero) Aryl Pentafluorobenzenesulfonates and Triflates using Palladium‐Cobalt Bimetallic Catalyst: Dual Role of Cobalt Carbonyl

Jayan T. Joseph, Ayyiliath M. Sajith, Revanna C. Ningegowda et al. · Advanced Synthesis & Catalysis · 2017 · 38 citations

Chemical Engineering, Cross-coupling Reaction, Engineering +15