Joonsun Lee

Directed evolution of CRISPR-Cas9 to increase its specificity

Jungjoon K. Lee, Euihwan Jeong, Joonsun Lee et al. · Nature Communications · 2018 · 516 citations · Full text

Autophagy Regulates Homeostasis of Pluripotency-Associated Proteins in hESCs

Yun-Hee Cho, Kyu-Min Han, Dong‐Kyu Kim et al. · Stem Cells · 2013 · 59 citations · Full text

Autophagy Regulates Homeostasis, Mitophagy, Ups Inhibition +13

Sniper2L is a high-fidelity Cas9 variant with high activity

Young-hoon Kim, Nahye Kim, Ikenna C. Okafor et al. · Nature Chemical Biology · 2023 · 49 citations · Full text

Ascl1 and Ngn2 convert mouse embryonic stem cells to neurons via functionally distinct paths

Gintautas Vainorius, Maria Novatchkova, Georg Michlits et al. · Nature Communications · 2023 · 34 citations · Full text

Induced Pluripotent Stem Cell, Neuroregeneration, Developmental Biology +13

Using Sniper-Cas9 to Minimize Off-target Effects of CRISPR-Cas9 Without the Loss of On-target Activity Via Directed Evolution

Joonsun Lee, Minhee Jung, Euihwan Jeong et al. · Journal of Visualized Experiments · 2019 · 20 citations · Full text

Truncated Sgrnas, Off-target Effect, Functional Genomics +14