Gintautas Vainorius

Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles

Georg Michlits, Julian Jude, Matthias Hinterndorfer et al. · Nature Methods · 2020 · 146 citations

Biology, Allelic Variant, Genetics +8

CRISPR-UMI: single-cell lineage tracing of pooled CRISPR–Cas9 screens

Georg Michlits, Maria Hubmann, Szu-Hsien Sam Wu et al. · Nature Methods · 2017 · 135 citations

Single-cell Genomics, Gene Editing, Genome Editing +4

Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

Nofar Mor, Yoach Rais, Daoud Sheban et al. · Cell stem cell · 2018 · 74 citations · Full text

Directed Evolution, Naive Pluripotency, Signal Recognition +1

ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers

Ramesh Yelagandula, Karin Stecher, Maria Novatchkova et al. · Nature Cell Biology · 2023 · 41 citations · Full text

Chromatin, Transcriptional Regulation, Developmental Biology +10

Ascl1 and Ngn2 convert mouse embryonic stem cells to neurons via functionally distinct paths

Gintautas Vainorius, Maria Novatchkova, Georg Michlits et al. · Nature Communications · 2023 · 34 citations · Full text

Induced Pluripotent Stem Cell, Neuroregeneration, Developmental Biology +13