Melanie J. Ludlow

Piezo1 integration of vascular architecture with physiological force

Jing Li, Bing Hou, Sarka Tumova et al. · Nature · 2014 · 1.2K citations · Full text

Mechanobiology, Engineering, Vascular Adaptation +9

Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance

Baptiste Rode, Jian Shi, Naima Endesh et al. · Nature Communications · 2017 · 289 citations · Full text

(−)‐Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels

Yasemin Akbulut, Hannah J. Gaunt, Katsuhiko Muraki et al. · Angewandte Chemie International Edition · 2015 · 196 citations · Full text

Trpc5 Channels, Cellular Physiology, Molecular Pharmacology +20

Yoda1 analogue (<scp>D</scp>ooku1) which antagonizes <scp>Y</scp>oda1‐evoked activation of <scp>P</scp>iezo1 and aortic relaxation

Elizabeth L. Evans, Kevin Cuthbertson, Naima Endesh et al. · British Journal of Pharmacology · 2018 · 194 citations · Full text

Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion

Nicola M. Blythe, Katsuhiko Muraki, Melanie J. Ludlow et al. · Journal of Biological Chemistry · 2019 · 165 citations · Full text