Melanie J. Ludlow

Piezo1 integration of vascular architecture with physiological force

Jing Li, Bing Hou, Sarka Tumova et al. · Nature · 2014 · 1.2K citations

Engineering, Bioengineering, Biomedical Engineering +15

Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance

Baptiste Rode, Jian Shi, Naima Endesh et al. · Nature Communications · 2017 · 305 citations · Full text

Life Sciences, Biophysics, Physiology +17

Yoda1 analogue (<scp>D</scp>ooku1) which antagonizes <scp>Y</scp>oda1‐evoked activation of <scp>P</scp>iezo1 and aortic relaxation

Elizabeth L. Evans, Kevin Cuthbertson, Naima Endesh et al. · British Journal of Pharmacology · 2018 · 209 citations · Full text

Life Sciences, Pharmacology, Physiology +16

(−)‐Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels

Yasemin Akbulut, Hannah J. Gaunt, Katsuhiko Muraki et al. · Angewandte Chemie International Edition · 2015 · 197 citations · Full text

Medicine, Oncology, Pharmacology +17

Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion

Nicola M. Blythe, Katsuhiko Muraki, Melanie J. Ludlow et al. · Journal of Biological Chemistry · 2019 · 174 citations · Full text

Life Sciences, Cell Biology, Physiology +16