Davide Malfacini

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

S P H Alexander, Arthur Christopoulos, Anthony P. Davenport et al. · British Journal of Pharmacology · 2023 · 379 citations · Full text

Drug Target, Peptide Science, System Pharmacology +16

Lack of beta-arrestin signaling in the absence of active G proteins

Manuel Grundmann, Nicole Merten, Davide Malfacini et al. · Nature Communications · 2018 · 363 citations · Full text

The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor

Rebecca L. Miller, Aaron A. Thompson, Claudio Trapella et al. · Structure · 2015 · 78 citations · Full text

Signal Transduction, Biochemistry, Functional Selectivity +9

Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist

Anna Rizzi, Maria Camilla Cerlesi, Chiara Ruzza et al. · Pharmacology Research & Perspectives · 2016 · 65 citations · Full text

Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq‐Signaling Inhibitor FR900359

Max Crüsemann, Raphael Reher, Isabella Schamari et al. · Angewandte Chemie International Edition · 2017 · 65 citations

Engineering, Molecular Regulation, Gq Inhibition +24