Kiyoko Kuwata

Thymidylate synthase as a determinant of pemetrexed sensitivity in non-small cell lung cancer

Ken Takezawa, Isamu Okamoto, Wataru Okamoto et al. · British Journal of Cancer · 2011 · 169 citations · Full text

Medicine, Oncology, Pharmacology +13

Activation of HER Family Signaling as a Mechanism of Acquired Resistance to ALK Inhibitors in EML4-ALK–Positive Non–Small Cell Lung Cancer

Junko Tanizaki, Isamu Okamoto, Takafumi Okabe et al. · Clinical Cancer Research · 2012 · 156 citations

Medicine, Oncology, Pharmacology +17

MET Tyrosine Kinase Inhibitor Crizotinib (PF-02341066) Shows Differential Antitumor Effects in Non-small Cell Lung Cancer According to MET Alterations

Junko Tanizaki, Isamu Okamoto, Kunio Okamoto et al. · Journal of Thoracic Oncology · 2011 · 125 citations · Full text

Medicine, Oncology, Pharmacology +17

<i>MET</i> amplification as a potential therapeutic target in gastric cancer

Hisato Kawakami, Isamu Okamoto, Tokuzo Arao et al. · Oncotarget · 2012 · 86 citations · Full text

Medicine, Molecular Biology, Oncology +14

Antitumor Action of the MET Tyrosine Kinase Inhibitor Crizotinib (PF-02341066) in Gastric Cancer Positive for <i>MET</i> Amplification

Wataru Okamoto, Isamu Okamoto, Tokuzo Arao et al. · Molecular Cancer Therapeutics · 2012 · 82 citations · Full text

Medicine, Oncology, Pharmacology +17