Takafumi Okabe

Activation of ERBB2 Signaling Causes Resistance to the EGFR-Directed Therapeutic Antibody Cetuximab

Kimio Yonesaka, Kreshnik Zejnullahu, Isamu Okamoto et al. · Science Translational Medicine · 2011 · 658 citations

Cetuximab Sensitivity, Oncology, Erbb2 Signaling +15

Differential Constitutive Activation of the Epidermal Growth Factor Receptor in Non–Small Cell Lung Cancer Cells Bearing<i>EGFR</i>Gene Mutation and Amplification

Takafumi Okabe, Isamu Okamoto, Kenji Tamura et al. · Cancer Research · 2007 · 179 citations

Pathology, Cell Growth, Tumor Biology +16

B7-H3 Negatively Modulates CTL-Mediated Cancer Immunity

Kimio Yonesaka, Koji Haratani, Shiki Takamura et al. · Clinical Cancer Research · 2018 · 160 citations

Activation of HER Family Signaling as a Mechanism of Acquired Resistance to ALK Inhibitors in EML4-ALK–Positive Non–Small Cell Lung Cancer

Junko Tanizaki, Isamu Okamoto, Takafumi Okabe et al. · Clinical Cancer Research · 2012 · 154 citations

Cetuximab Response of Lung Cancer–Derived EGF Receptor Mutants Is Associated with Asymmetric Dimerization

Jeonghee Cho, Liang Chen, Naveen F. Sangji et al. · Cancer Research · 2013 · 117 citations · Full text

Medicine, Cetuximab Response, Cancer Cell Biology +13