Sarah J. Mancini

The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

Simon A. Hawley, Rebecca J. Ford, Brennan K. Smith et al. · Diabetes · 2016 · 386 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms

Sarah J. Mancini, D. H. A. Boyd, Omar J. Katwan et al. · Scientific Reports · 2018 · 235 citations · Full text

Life Sciences, Cardiology, Pharmacology +17

Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling

Claire Rutherford, Claire Speirs, Jamie J.L. Williams et al. · Science Signaling · 2016 · 103 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation

Sarah J. Mancini, Anna White, Silvia Bijland et al. · Molecular and Cellular Endocrinology · 2016 · 101 citations · Full text

Life Sciences, Biochemistry, Physiology +17

Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487

Helen R. Heathcote, Sarah J. Mancini, Anastasiya Strembitska et al. · Biochemical Journal · 2016 · 72 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13