Henrik Keränen

High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C

Hanna Willander, Glareh Askarieh, Michael Landreh et al. · Proceedings of the National Academy of Sciences · 2012 · 125 citations · Full text

Acylguanidine Beta Secretase 1 Inhibitors: A Combined Experimental and Free Energy Perturbation Study

Henrik Keränen, Laura Pérez‐Benito, Myriam Ciordia et al. · Journal of Chemical Theory and Computation · 2017 · 92 citations

Core Hopping Fep+, Peptide Science, Pharmacotherapy +16

Predicting Binding Free Energies of PDE2 Inhibitors. The Difficulties of Protein Conformation

Laura Pérez‐Benito, Henrik Keränen, Herman van Vlijmen et al. · Scientific Reports · 2018 · 65 citations · Full text

Structural and Energetic Effects of A2A Adenosine Receptor Mutations on Agonist and Antagonist Binding

Henrik Keränen, Hugo Gutiérrez‐de‐Terán, Johan Åqvist · PLoS ONE · 2014 · 56 citations · Full text

Computational Identification of Uncharacterized Cruzain Binding Sites

Jacob D. Durrant, Henrik Keränen, Benjamin A. Wilson et al. · PLoS neglected tropical diseases · 2010 · 54 citations · Full text

Drug Target, Engineering, Structural Bioinformatics +17