Chengfei Ruan

Solvent-Induced Protein Precipitation for Drug Target Discovery on the Proteomic Scale

Xiaolei Zhang, Qi Wang, Yanan Li et al. · Analytical Chemistry · 2019 · 105 citations

A peptide-centric local stability assay enables proteome-scale identification of the protein targets and binding regions of diverse ligands

Kejia Li, Shijie Chen, Keyun Wang et al. · Nature Methods · 2024 · 45 citations

Proteomic Technology, Protein Targets, Protein Function +13

Matrix Thermal Shift Assay for Fast Construction of Multidimensional Ligand–Target Space

Chengfei Ruan, Yan Wang, Xiaolei Zhang et al. · Analytical Chemistry · 2022 · 36 citations

Highly effective identification of drug targets at the proteome level by pH-dependent protein precipitation

Xiaolei Zhang, Keyun Wang, Sijin Wu et al. · Chemical Science · 2022 · 33 citations · Full text

Drug Target, Molecular Biology, Target Space +20

Precipitate-Supported Thermal Proteome Profiling Coupled with Deep Learning for Comprehensive Screening of Drug Target Proteins

Chengfei Ruan, Wanshan Ning, Zhen Liu et al. · ACS Chemical Biology · 2022 · 30 citations