Mike Miller

Discovery of 3-{5-[(6-Amino-1<i>H</i>-pyrazolo[3,4-<i>b</i>]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor with Improved Potency against Key Mutant Viruses

Thomas J. Tucker, John T. Sisko, Robert M. Tynebor et al. · Journal of Medicinal Chemistry · 2008 · 132 citations · Full text

Molecular Biology, Key Mutant Viruses, Pharmacotherapy +20

The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations

Thomas J. Tucker, Sandeep Saggar, John T. Sisko et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 60 citations · Full text

Medicinal Chemistry, Medicine, Natural Sciences +12

Design and Synthesis of Conformationally Constrained Inhibitors of Non-Nucleoside Reverse Transcriptase

Robert Gomez, Samson J. Jolly, Theresa M. Williams et al. · Journal of Medicinal Chemistry · 2011 · 40 citations · Full text

Molecular Biology, Pharmacotherapy, Antiviral Drug +22

Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants

Dai‐Shi Su, John J. Lim, Elizabeth Tinney et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 39 citations · Full text

Biochemistry, Medicine, Drug Discovery +7

Biaryl Ethers as Novel Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Key Mutant Viruses

Dai‐Shi Su, John J. Lim, Elizabeth Tinney et al. · Journal of Medicinal Chemistry · 2009 · 36 citations · Full text

Viral Replication, Molecular Biology, Key Mutant Viruses +19