R.A. Powers

Structure-Based Approach for Binding Site Identification on AmpC β-Lactamase

R.A. Powers, Brian K. Shoichet · Journal of Medicinal Chemistry · 2002 · 135 citations · Full text

Bioorganic Chemistry, Structural Bioinformatics, Biomolecular Structure Prediction +16

Structure-Based Discovery of a Novel, Noncovalent Inhibitor of AmpC β-Lactamase

R.A. Powers, Federica Morandi, Brian K. Shoichet · Structure · 2002 · 117 citations · Full text

Biochemistry, Medicine, Structure-based Discovery +8

Structures of Ceftazidime and Its Transition-State Analogue in Complex with AmpC β-Lactamase:  Implications for Resistance Mutations and Inhibitor Design^,

R.A. Powers, Emilia Caselli, Pamela J. Focia et al. · Biochemistry · 2001 · 114 citations · Full text

Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam

Kip-Chumba J. Kaitany, Neil V. Klinger, Cynthia M. June et al. · Antimicrobial Agents and Chemotherapy · 2013 · 90 citations · Full text

Bioorganic Chemistry, Mechanistic Basis, Antimicrobial Chemotherapy +16

Energetic, structural, and antimicrobial analyses of β-lactam side chain recognition by β-lactamases

Emilia Caselli, R.A. Powers, Larry C Blasczcak et al. · Chemistry & Biology · 2001 · 85 citations · Full text

Antimicrobial Drug Discovery, Bioorganic Chemistry, Antimicrobial Susceptibility +12