ERK-mediated regulation of leukotriene biosynthesis by androgens: A molecular basis for gender differences in inflammation and asthma

Carlo Pergola, Gabriele Dodt, Antonietta Rossi, +7

Proceedings of the National Academy of Sciences

AsthmaInflammatory Lung DiseaseLipid PeroxidationImmunologyLt Biosynthesis Capacity +21

Inhibition of nitric oxide biosynthesis by anthocyanin fraction of blackberry extract

Carlo Pergola, Antonietta Rossi, Paola Dugo, +2

Nitric Oxide

BiosynthesisNitric Oxide BiosynthesisEngineeringBiochemistryReactive Nitrogen Specie +9

The 5‐lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages

Antonietta Rossi, Carlo Pergola, Andreas Koeberle, +6

British Journal of Pharmacology

Mannosylation of LNP Results in Improved Potency for Self-Amplifying RNA (SAM) Vaccines

Roshan Goswami, Despo Chatzikleanthous, Gustavo Lou, +11

ACS Infectious Diseases

Myrtucommulone from Myrtus communis Exhibits Potent Anti-Inflammatory Effectiveness in Vivo

Antonietta Rossi, Rosanna Di Paola, Emanuela Mazzon, +8

Journal of Pharmacology and Experimental Therapeutics

Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males

Simona Pace, Carlo Pergola, Friederike Dehm, +15

Journal of Clinical Investigation

Lipid PeroxidationImmunologyFemale Reproductive FunctionReproductive BiologyOxidative Stress +17

Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes

Carlo Pergola, Anja Rogge, Gabriele Dodt, +6

The FASEB Journal

Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1)

Gianluigi Lauro, Maria Strocchia, Stefania Terracciano, +6

European Journal of Medicinal Chemistry

Medicinal ChemistryAnti-inflammatoryBioorganic ChemistryBiochemistryNatural Sciences +8

The molecular mechanism of the inhibition by licofelone of the biosynthesis of 5‐lipoxygenase products

Lutz Fischer, Michael Hörnig, Carlo Pergola, +6

British Journal of Pharmacology

Structural Optimization and Biological Evaluation of 2-Substituted 5-Hydroxyindole-3-carboxylates as Potent Inhibitors of Human 5-Lipoxygenase

Eva-Maria Karg, Susann Luderer, Carlo Pergola, +6

Journal of Medicinal Chemistry

Pharmaceutical Science2-Substituted 5-Hydroxyindole-3-carboxylatesLipid PeroxidationStructural OptimizationChemical Biology +14