Jing‐Rui Chai

Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a κ Partial Agonist and μ Partial Agonist

Yuhua Wang, Jing‐Rui Chai, Xuejun Xu et al. · Scientific Reports · 2018 · 51 citations · Full text

Pain Disorders, Pharmacological Characterization, Pain Medicine +24

Amygdalar κ-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence

Gui‐Ying Zan, Yujun Wang, Xueping Li et al. · Cell Reports · 2021 · 28 citations · Full text

Affective Neuroscience, Psychopharmacology, Transporter 1 +21

Amygdala dynorphin/κ opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress

Gui‐Ying Zan, Xiang Sun, Yujun Wang et al. · Acta Pharmacologica Sinica · 2021 · 21 citations · Full text

Psychoneuroimmunology, Psychiatry, Behavioral Neuroscience +10

Dissociative role for dorsal hippocampus in mediating heroin self‐administration and relapse through CDK5 and RhoB signaling revealed by proteomic analysis

Zhong‐Guo Chen, Xing Liu, Weisheng Wang et al. · Addiction Biology · 2016 · 19 citations

Neurotransmitter, Synaptic Signaling, Heroin Self‐administration +17

Discovery of an <i>M</i>-Substituted <i>N</i>-Cyclopropylmethyl-7α-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active κ-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile

He Qian, Yuanyuan Wei, Xiao Liu et al. · Journal of Medicinal Chemistry · 2021 · 16 citations · Full text