Cassie Kline

Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer

Francesca Petralia, Nicole Tignor, Boris Reva et al. · Cell · 2020 · 344 citations · Full text

Medicine, Cancer Biology, Oncology +17

Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy

Cassie Kline, Nancy M. Joseph, James P. Grenert et al. · Neuro-Oncology · 2016 · 233 citations · Full text

Medicine, Molecular Genetics, Oncology +17

Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201

Rohinton S. Tarapore, Matthew D. Hall, Nicole Shonka et al. · Journal of Neuro-Oncology · 2019 · 197 citations

Medicine, Oncology, Pharmacology +9

Clinically Relevant and Minimally Invasive Tumor Surveillance of Pediatric Diffuse Midline Gliomas Using Patient-Derived Liquid Biopsy

Eshini Panditharatna, Lindsay Kilburn, Mariam Aboian et al. · Clinical Cancer Research · 2018 · 195 citations · Full text

Medicine, Oncology, Pediatrics +17

The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial

Lindsay Kilburn, Dong-Anh Khuong-Quang, Jordan R. Hansford et al. · Nature Medicine · 2023 · 177 citations · Full text

Medicine, Oncology, Pharmacology +15