R. H. Hutchings - Concepedia

Author

R. H. Hutchings

Also Known As

R. H Hutchings, R. H. HUTCHINGS, R. H. Hutchings, R. HUTCHINGS, R.H. Hutchings, RICHARD H. HUTCHINGS, Richard H Hutchings, Richard H. Hutchings, Richard Hutchings

125

Publications

483

Citations

H-Index

Concepts

All Affiliations

Pfizer (United States)Colorado State University Johns Hopkins University

About

R. H. Hutchings is an author at Pfizer (United States) specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	8	8	343
2	Biochemistry	7	7	321
3	Natural Sciences	3	3	203
4	Engineering	1	1	10
5	Biomolecular Engineering	1	1	10

R. H. Hutchings

Publications

433

Citations

H-Index

Page 1

	Year	Citations
Antiproliferative Hybrid Analogs of the Hormone 1α,25-Dihydroxyvitamin D<sub>3</sub>: Design, Synthesis, and Preliminary Biological Evaluation Gary H. Posner, Jae Kyoo Lee, M. Christina White, The Journal of Organic Chemistry Medicinal ChemistryPreliminary Biological EvaluationOxysterolBiochemistryConjugate Base	1997	81
Thermodynamic and Structure Guided Design of Statin Based Inhibitors of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Ronald W. Sarver, Elizabeth Bills, Gary L. Bolton, Journal of Medicinal Chemistry Medicinal ChemistryBiochemistryCardiovascular DiseaseStructure Guided DesignStatin Inhibitors	2008	64
Substituted Pyrazoles as Hepatoselective HMG-CoA Reductase Inhibitors: Discovery of (3<i>R</i>,5<i>R</i>)-7-[2-(4-Fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2<i>H</i>-pyrazol-3-yl]-3,5-dihydroxyheptanoic Acid (PF-3052334) as a Candidate for the Treatment of Hypercholesterolemia Jeffrey A. Pfefferkorn, Chulho Choi, Scott D. Larsen, Journal of Medicinal Chemistry Molecular PharmacologyMedicinal ChemistrySubstituted PyrazolesHmg-coa Reductase InhibitorsAldo-keto Reductase	2007	58
An Oxazoline-Mediated Synthesis of the Pyrrolophenanthridine Alkaloids and Some Novel Derivatives R. H. Hutchings, A. I. MEYERS The Journal of Organic Chemistry N-benzyl-7-bromoindoline 25HeterocyclicIntermediate BiarylBiochemistryOxazoline-mediated Synthesis	1996	55
The asymmetric synthesis of 1-alkyl-2,3,4,5-tetrahydro-benzazepines and benzo[β]-1-azabicyclo[5,3,1]decanes A. I. MEYERS, R. H. Hutchings Tetrahedron Organic ChemistryAsymmetric SynthesisHeterocyclicChemistry	1993	54
Discovery of biaryl carboxylamides as potent RORγ inverse agonists Jianhua Chao, Istvan Enyedy, Kurt van Vloten, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyMedicinal ChemistryMedicineBiaryl CarboxylamidesMechanism Of Action	2015	37
Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: A bench-to-bedside case study on tissue selective drug distribution Jeffrey A. Pfefferkorn, John Litchfield, R. H. Hutchings, Bioorganic & Medicinal Chemistry Letters OxysterolBiochemistryMedicineBench-to-bedside Case StudyHyperlipidemia	2010	26
A total synthesis of the pyrrolophenthridone alkaloid oxoassoanine A. I. MEYERS, R. H. Hutchings Tetrahedron Letters BiochemistryTotal SynthesisOrganic ChemistryNatural Product SynthesisSynthetic Chemistry	1993	26
Arylpiperazine substituted heterocycles as Selective α1a adrenergic antagonists Haripada Khatuya, R. H. Hutchings, Gee‐Hong Kuo, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyBiochemistryMedicineMechanism Of ActionPharmacological Agent	2002	11
AN OVERVIEW OF SYNTHETIC STUDIES OF ANTIBIOTICS FROM MYXOBACTERIA David R. Williams, Jie Jack Li, R. H. Hutchings Organic Preparations and Procedures International AntibioticsAntibacterial AgentAntimicrobial TherapyMicrobiologyAntimicrobial Chemotherapy	2000	11

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