R. H. Hutchings

Antiproliferative Hybrid Analogs of the Hormone 1α,25-Dihydroxyvitamin D₃:  Design, Synthesis, and Preliminary Biological Evaluation

Gary H. Posner, Jae Kyoo Lee, M. Christina White et al. · The Journal of Organic Chemistry · 1997 · 81 citations

Medicinal Chemistry, Preliminary Biological Evaluation, Oxysterol +13

Thermodynamic and Structure Guided Design of Statin Based Inhibitors of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase

Ronald W. Sarver, Elizabeth Bills, Gary L. Bolton et al. · Journal of Medicinal Chemistry · 2008 · 64 citations · Full text

Medicinal Chemistry, Biochemistry, Cardiovascular Disease +15

Substituted Pyrazoles as Hepatoselective HMG-CoA Reductase Inhibitors: Discovery of (3<i>R</i>,5<i>R</i>)-7-[2-(4-Fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2<i>H</i>-pyrazol-3-yl]-3,5-dihydroxyheptanoic Acid (PF-3052334) as a Candidate for the Treatment of Hypercholesterolemia

Jeffrey A. Pfefferkorn, Chulho Choi, Scott D. Larsen et al. · Journal of Medicinal Chemistry · 2007 · 58 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Substituted Pyrazoles +15

An Oxazoline-Mediated Synthesis of the Pyrrolophenanthridine Alkaloids and Some Novel Derivatives

R. H. Hutchings, A. I. MEYERS · The Journal of Organic Chemistry · 1996 · 55 citations

N-benzyl-7-bromoindoline 25, Heterocyclic, Intermediate Biaryl +12

The asymmetric synthesis of 1-alkyl-2,3,4,5-tetrahydro-benzazepines and benzo[β]-1-azabicyclo[5,3,1]decanes

A. I. MEYERS, R. H. Hutchings · Tetrahedron · 1993 · 54 citations

Organic Chemistry, Asymmetric Synthesis, Heterocyclic +1