Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth

Sonja Kleffel, Christian Posch, Steven R. Barthel, +19

Cell

Cancer ImmunosurveillanceMelanomaMedicineCell BiologyTumor Microenvironment +1

Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo

Christian Posch, Homayoun Moslehi, Luzviminda Feeney, +11

Proceedings of the National Academy of Sciences

Combined immunotherapy with nivolumab and ipilimumab with and without local therapy in patients with melanoma brain metastasis: a DeCOG* study in 380 patients

Teresa Amaral, Felix Kiecker, Sarah Schaefer, +27

Journal for ImmunoTherapy of Cancer

DNA and aptamer stabilized gold nanoparticles for targeted delivery of anticancer therapeutics

Alfonso Latorre, Christian Posch, Yolanda Garcimartín, +8

Nanoscale

NanoparticlesNanotherapeuticsEngineeringTargeted DeliveryBiomedical Engineering +14

Comparative profile of cutaneous adverse events: BRAF/MEK inhibitor combination therapy versus BRAF monotherapy in melanoma

Martina Sanlorenzo, Aditi Choudhry, Igor Vujic, +10

Journal of the American Academy of Dermatology

Skin CancerComparative ProfileMedicinePhotocarcinogenesisMelanoma +4

The role of wide local excision for the treatment of severe hidradenitis suppurativa (Hurley grade III): Retrospective analysis of 74 patients

Christian Posch, Babak Itzinger-Monshi, Tamara Quint, +3

Journal of the American Academy of Dermatology

Wide Local ExcisionSevere Hidradenitis SuppurativaRetrospective AnalysisClinical DermatologySurgery +3

Metformin and trametinib have synergistic effects on cell viability and tumor growth in<i>NRAS</i>mutant cancer

Igor Vujic, Martina Sanlorenzo, Christian Posch, +7

Oncotarget

Efficacy of intravenous immunoglobulins in livedoid vasculopathy: Long-term follow-up of 11 patients

Babak Itzinger-Monshi, Christian Posch, Igor Vujic, +3

Journal of the American Academy of Dermatology

RheumatologyVasculitisImmunologyIntravenous ImmunoglobulinsTransplant Arteriopathy +4

Combined Inhibition of MEK and Plk1 Has Synergistic Antitumor Activity in NRAS Mutant Melanoma

Christian Posch, Brian D. Cholewa, Igor Vujic, +9

Journal of Investigative Dermatology

MedicineMelanomaImmune Checkpoint InhibitorCancer BiologyNras Mutant Melanoma +5

Clinical impact of COVID-19 on patients with cancer treated with immune checkpoint inhibition

Aljosja Rogiers, Inês Pires da Silva, Chiara Tentori, +46

Journal for ImmunoTherapy of Cancer