Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma

Christine G. Lian, Yufei Xu, Craig J. Ceol, +27

Cell

ChromatinPhotocarcinogenesisMelanomaEpigenetic HallmarkMedicine +4

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth

Sonja Kleffel, Christian Posch, Steven R. Barthel, +19

Cell

Cancer ImmunosurveillanceMelanomaMedicineCell BiologyTumor Microenvironment +1

Tumor Dormancy and Cancer Stem Cells: Two Sides of the Same Coin?

Sonja Kleffel, Tobias Schatton

Advances in experimental medicine and biology

Lineage PlasticityTumor DormancyMedicineAdult Stem CellBiological Microenvironments +11

Long-Term Heart Transplant Survival by Targeting the Ionotropic Purinergic Receptor P2X7

Andrea Vergani, Sara Tezza, Francesca D’Addio, +19

Circulation

Interleukin-10+ Regulatory B Cells Arise Within Antigen-Experienced CD40+ B Cells to Maintain Tolerance to Islet Autoantigens

Sonja Kleffel, Andrea Vergani, Sara Tezza, +13

Diabetes

ABCB5 Identifies Immunoregulatory Dermal Cells

Tobias Schatton, Jun Yang, Sonja Kleffel, +21

Cell Reports

Combined Inhibition of MEK and Plk1 Has Synergistic Antitumor Activity in NRAS Mutant Melanoma

Christian Posch, Brian D. Cholewa, Igor Vujic, +9

Journal of Investigative Dermatology

MedicineMelanomaImmune Checkpoint InhibitorCancer BiologyNras Mutant Melanoma +5

IL-21 Is an Antitolerogenic Cytokine of the Late-Phase Alloimmune Response

Alessandra Petrelli, Michele Carvello, Andrea Vergani, +14

Diabetes

Improved Function of Circulating Angiogenic Cells Is Evident in Type 1 Diabetic Islet-Transplanted Patients

Alessandra Petrelli, Anna Maestroni, Gian Paolo Fadini, +12

American Journal of Transplantation

Type 1Islet TransplantationDiabetic Islet-transplanted PatientsTransplantationDiabetes +9

ABCB5-Targeted Chemoresistance Reversal Inhibits Merkel Cell Carcinoma Growth

Sonja Kleffel, Nayoung Lee, Cecilia Lezcano, +15

Journal of Investigative Dermatology