Nrf2 Suppresses Oxidative Stress and Inflammation in<i>App</i>Knock-In Alzheimer’s Disease Model Mice

Akira Uruno, Daisuke Matsumaru, Rie Ryoke, +7

Molecular and Cellular Biology

Progenitor Cell Expansion and Organ Size of Mouse Adrenal Is Regulated by Sonic Hedgehog

Chen‐Che Jeff Huang, Shinichi Miyagawa, Daisuke Matsumaru, +2

Endocrinology

Human GrowthMammalian PhysiologyAdrenal CapsuleGlucocorticoidCellular Physiology +21

Dosage-dependent hedgehog signals integrated with Wnt/β-catenin signaling regulate external genitalia formation as an appendicular program

Shinichi Miyagawa, Anne Moon, Ryuma Haraguchi, +12

Development

Developmental BiologySignal TransductionFgf8 ExpressionSignaling PathwayGrowth Factor +13

Mouse Shh is required for prechordal plate maintenance during brain and craniofacial morphogenesis

Kazushi Aoto, Yayoi Shikata, Hajime Imai, +5

Developmental Biology

Knockout MouseDevelopmental BiologyBrain DevelopmentNeuroanatomyCraniofacial Development +10

Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers

Keito Okazaki, Hayato Anzawa, Zun Liu, +18

Nature Communications

The Role of Sonic Hedgehog-Gli2 Pathway in the Masculinization of External Genitalia

Shinichi Miyagawa, Daisuke Matsumaru, Aki Murashima, +8

Endocrinology

GeneticsGynecologyExternal GenitaliaReproductive BiologyEpigenetics +15

Ptch1-mediated dosage-dependent action of Shh signaling regulates neural progenitor development at late gestational stages

Yayoi Shikata, Toshiaki Okada, Mitsuhiro Hashimoto, +6

Developmental Biology

Developmental BiologyNeural Progenitor DevelopmentBrain DevelopmentLate Gestational StagesNeuroscience +8

Dysregulation of Wnt inhibitory factor 1 (Wif1) expression resulted in aberrant Wnt-β-catenin signaling and cell death of the cloaca endoderm, and anorectal malformations

Roy Chun-Laam Ng, Daisuke Matsumaru, Adrian Ho, +7

Cell Death and Differentiation

Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss

Tetsuya Oishi, Daisuke Matsumaru, Nao Ota, +5

npj Aging and Mechanisms of Disease

Gene transduction by sonoporation

Sho Ohta, Kentaro Suzuki, Yukiko Ogino, +4

Development Growth & Differentiation

Developmental BiologyTissue DevelopmentEngineeringGene TransductionMedicine +13