Ningbo Cai

Inhibition of PDE4 protects neurons against oxygen-glucose deprivation-induced endoplasmic reticulum stress through activation of the Nrf-2/HO-1 pathway

Bingtian Xu, Yunyun Qin, Dan Li et al. · Redox Biology · 2019 · 120 citations · Full text

Cell Death, Er Stress, Redox Biology +22

Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway

Bingtian Xu, Jiangping Xu, Ningbo Cai et al. · Free Radical Biology and Medicine · 2020 · 85 citations

Ire1α/traf2/jnk Pathway, Gsk3β-mediated Oxidative Stress, Ischemic Stroke +11

FCPR03, a novel phosphodiesterase 4 inhibitor, alleviates cerebral ischemia/reperfusion injury through activation of the AKT/GSK3β/ β-catenin signaling pathway

Bingtian Xu, Tiantian Wang, Jiao Xiao et al. · Biochemical Pharmacology · 2019 · 61 citations

Inflammation, Neuroinflammation, Ischemic Stroke +13

Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats

Bingtian Xu, Mengfan Li, Ke-chun Chen et al. · Acta Pharmacologica Sinica · 2022 · 31 citations · Full text

Cerebral Ischemia, Cerebral Vascular Regulation, Neuropharmacology +8

Roflupram, a novel phosphodiesterase 4 inhibitor, inhibits lipopolysaccharide-induced neuroinflammatory responses through activation of the AMPK/Sirt1 pathway

Dan Li, Jiangping Xu, Yunyun Qin et al. · International Immunopharmacology · 2020 · 19 citations

Inflammation, Anti-inflammatory, Signal Transduction +15