Bingtian Xu

Inhibition of PDE4 protects neurons against oxygen-glucose deprivation-induced endoplasmic reticulum stress through activation of the Nrf-2/HO-1 pathway

Bingtian Xu, Yunyun Qin, Dan Li et al. · Redox Biology · 2019 · 120 citations · Full text

Cell Death, Er Stress, Redox Biology +22

Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway

Bingtian Xu, Jiangping Xu, Ningbo Cai et al. · Free Radical Biology and Medicine · 2020 · 85 citations

Ire1α/traf2/jnk Pathway, Gsk3β-mediated Oxidative Stress, Ischemic Stroke +11

FCPR03, a novel phosphodiesterase 4 inhibitor, alleviates cerebral ischemia/reperfusion injury through activation of the AKT/GSK3β/ β-catenin signaling pathway

Bingtian Xu, Tiantian Wang, Jiao Xiao et al. · Biochemical Pharmacology · 2019 · 61 citations

Inflammation, Neuroinflammation, Ischemic Stroke +13

Inhibition of PDE4 by FCPR16 induces AMPK-dependent autophagy and confers neuroprotection in SH-SY5Y cells and neurons exposed to MPP+-induced oxidative insult

Jiahong Zhong, Jinfeng Xie, Xiao Jiao et al. · Free Radical Biology and Medicine · 2019 · 46 citations

Sh-sy5y Cells, Mitophagy, Neurodegenerative Diseases +13

Mitofusin 2 confers the suppression of microglial activation by cannabidiol: Insights from in vitro and in vivo models

Mengfan Li, Bingtian Xu, Xing Li et al. · Brain Behavior and Immunity · 2022 · 33 citations

Inflammation, Vivo Models, Microglial Activation +9