Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation

Hiromi Iwasaki, Chamorro Somoza, Hirokazu Shigematsu, +15

Blood

Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis

Yojiro Arinobu, Hiromi Iwasaki, Michael F. Gurish, +6

Proceedings of the National Academy of Sciences

Reciprocal Activation of GATA-1 and PU.1 Marks Initial Specification of Hematopoietic Stem Cells into Myeloerythroid and Myelolymphoid Lineages

Yojiro Arinobu, Shin-ichi Mizuno, Yong Chong, +8

Cell stem cell

Developmental BiologyReciprocal ActivationMedicineGeneticsStem Cell Mobilization +11

The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages

Hiromi Iwasaki, Shin-ichi Mizuno, Yojiro Arinobu, +6

Genes & Development

Lymphocyte DevelopmentGeneticsLineage SpecificationMolecular GeneticsMultipotent Stem Cells +18

Identification of eosinophil lineage–committed progenitors in the murine bone marrow

Hiromi Iwasaki, Shin-ichi Mizuno, Robin Mayfield, +6

The Journal of Experimental Medicine

Cutting edge: dominant effect of Ile50Val variant of the human IL-4 receptor alpha-chain in IgE synthesis.

Hiromichi Mitsuyasu, Yukiyoshi Yanagihara, Xiao Quan Mao, +12

PubMed

AsthmaInflammatory Lung DiseaseImmunologyImmune RegulationImmunotherapy +17

Association of tumor necrosis factor receptor type II polymorphism 196R with systemic lupus erythematosus in the Japanese: Molecular and functional analysis

Chika Morita, Takahiko Horiuchi, Hiroshi Tsukamoto, +8

Arthritis & Rheumatism

Cutting Edge: Dominant Effect of Ile50Val Variant of the Human IL-4 Receptor α-Chain in IgE Synthesis

Hiromichi Mitsuyasu, Yukiyoshi Yanagihara, Xiao‐Quan Mao, +12

The Journal of Immunology

AsthmaImmunodeficienciesImmune RegulationImmunologyCd4 T Cell Responses +18

MAP Kinase Pathways as a Route for Regulatory Mechanisms of IL-10 and IL-4 Which Inhibit COX-2 Expression in Human Monocytes

Hiroaki Niiro, Takeshi Otsuka, Eiichi Ogami, +7

Biochemical and Biophysical Research Communications

InflammationCytokineSignal TransductionAutoimmune DiseaseMap Kinase Pathways +12

Antagonistic Effects of an Alternative Splice Variant of Human IL-4, IL-4δ2, on IL-4 Activities in Human Monocytes and B Cells

Yojiro Arinobu, Sergei P. Atamas, Takeshi Otsuka, +7

Cellular Immunology

InflammationCytokineAutoimmune DiseaseLymphocyte DevelopmentImmune Cell Development +8