Insulin treatment attenuates renal ADAM17 and ACE2 shedding in diabetic Akita mice

Esam Salem, Nadja Grobe, Khalid M. Elased

American Journal of Physiology-Renal Physiology

Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney

Oliver Domenig, Arndt Manzel, Nadja Grobe, +14

Scientific Reports

Simulation of Pool Testing to Identify Patients With Coronavirus Disease 2019 Under Conditions of Limited Test Availability

Alhaji Cherif, Nadja Grobe, Xiaoling Wang, +1

JAMA Network Open

Coronavirus Disease 2019Point-of-care TestingLimited Test AvailabilityDiagnostic TestCovid-19 Pandemic +8

Rosiglitazone Treatment of Type 2 Diabetic db/db Mice Attenuates Urinary Albumin and Angiotensin Converting Enzyme 2 Excretion

Harshita Chodavarapu, Nadja Grobe, Hari K. Somineni, +3

PLoS ONE

Renal PathologyInsulin SignalingOxidative StressMetabolic SyndromeRenal Function +20

Reduced thrombosis in Klkb1−/− mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor

Evi X. Stavrou, Chao Fang, Alona Merkulova, +5

Blood

Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2−/− mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation

Chao Fang, Evi X. Stavrou, Alec A. Schmaier, +11

Blood

The biosynthesis of papaverine proceeds via (S)-reticuline

Xu Han, Marc Lamshöft, Nadja Grobe, +5

Phytochemistry

BiosynthesisBioorganic ChemistryBiochemistryNatural SciencesPapaverine Proceeds +3

Increased urinary angiotensin converting enzyme 2 and neprilysin in patients with type 2 diabetes

Sridevi Gutta, Nadja Grobe, Meenasri Kumbaji, +4

American Journal of Physiology-Renal Physiology

HypertensionImmunologyPathologyUrinary AngiotensinTranslational Medicine +16

Mass spectrometry for the molecular imaging of angiotensin metabolism in kidney

Nadja Grobe, Khalid M. Elased, David R. Cool, +1

American Journal of Physiology-Endocrinology and Metabolism

Mammalian Cytochrome P450 Enzymes Catalyze the Phenol-coupling Step in Endogenous Morphine Biosynthesis

Nadja Grobe, Baichen Zhang, Ursula Fisinger, +3

Journal of Biological Chemistry