Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease

Elisa Giacomelli, Viviana Meraviglia, Giulia Campostrini, +26

Cell stem cell

Common and rare variant associations with clonal haematopoiesis phenotypes

Michael D. Kessler, Amy Damask, Sean O’Keeffe, +40

Nature

Allelic VariantRare Variant AssociationsHematologyPathologyVariant Interpretation

Characterization of directed differentiation by high-throughput single-cell RNA-Seq

Magali Soumillon, Davide Cacchiarelli, Stefan Semrau, +2

EngineeringGene Expression ProfilingDirected DifferentiationSingle Cell SequencingStem Cells +14

Differential Stoichiometry among Core Ribosomal Proteins

Nikolai Slavov, Stefan Semrau, Edoardo M. Airoldi, +2

Cell Reports

Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells

Stefan Semrau, Johanna Goldmann, Magali Soumillon, +3

Nature Communications

Lineage PlasticityCell LineageFunctional GenomicsDevelopmental BiologySingle Cell Sequencing +12

Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development

Mazène Hochane, Patrick R. van den Berg, Xueying Fan, +7

PLoS Biology

Transcriptomics TechnologyEmbryologySingle Cell SequencingMammalian Kidney DevelopmentKidney Tubule Remodeling +14

Accurate Determination of Elastic Parameters for Multicomponent Membranes

Stefan Semrau, Timon Idema, Laurent Holtzer, +2

Physical Review Letters

Deciphering Metabolic Heterogeneity by Single-Cell Analysis

Tom M. J. Evers, Mazène Hochane, Sander J. Tans, +4

Analytical Chemistry

Metabolic HeterogeneityBiological Mass SpectrometryTrajectory AnalysisMetabolic NetworkIndividual Cells +16

Membrane heterogeneity – from lipid domains to curvature effects

Stefan Semrau, Thomas Schmidt

Soft Matter

Membrane StructureLipid BiophysicsEngineeringAnalytical UltracentrifugationLipid Movement +20

Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs

Yuelin Song, Patrick R. van den Berg, Styliani Markoulaki, +10

Molecular Cell

ChromatinTranscriptional RegulationChromatin RemodelingCellular HeterogeneityNatural Sciences +9