Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA

Anand Srivastava, Stéphane Gangnard, Adam Round, +13

Proceedings of the National Academy of Sciences

Full-length Extracellular RegionMalariaImmunologyMolecular BiologyPregnancy-associated Malaria +19

PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a first-in-human, randomised, double-blind, placebo-controlled study

Sodiomon B. Sirima, Laura Richert, Arnaud Chêne, +35

The Lancet Infectious Diseases

VaccinationVaccinologyMaternal ImmunizationVaccine DevelopmentMalaria +7

Influence of the Timing of Malaria Infection during Pregnancy on Birth Weight and on Maternal Anemia in Benin

Bich-Tram Huynh, Nadine Fiévet, Gildas Gbaguidi, +7

American Journal of Tropical Medicine and Hygiene

Disruption of Var2csa Gene Impairs Placental Malaria Associated Adhesion Phenotype

Nicola K. Viebig, Emily Levin, Sébastien Dechavanne, +5

PLoS ONE

Maternal ImmunizationGeneticsMalariaImmunologyPathogenesis +9

Var2CSA Minimal CSA Binding Region Is Located within the N-Terminal Region

Anand Srivastava, Stéphane Gangnard, Sébastien Dechavanne, +4

PLoS ONE

Csa BindingSingle Csa-binding SiteProtein FunctionMedicineCell Adhesion +10

Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP

Darya V. Urusova, Lenore L. Carias, Yining Huang, +11

Nature Microbiology

MalariaImmunologyVector-parasite RelationshipMolecular BiologyAntibody Screening +8

Placental Cytokine and Chemokine Profiles Reflect Pregnancy Outcomes in Women Exposed to Plasmodium falciparum Infection

Arnaud Chêne, Valérie Briand, Samad Ibitokou, +6

Infection and Immunity

MalariaImmunologyReproductive HealthGynecologyPregnancy-associated Malaria +20

Var2CSA DBL6-epsilon domain expressed in HEK293 induces limited cross-reactive and blocking antibodies to CSA binding parasites

Pablo Fernández, Nicola K. Viebig, Sébastien Dechavanne, +4

Malaria Journal

Antibodies to a Full-Length VAR2CSA Immunogen Are Broadly Strain-Transcendent but Do Not Cross-Inhibit Different Placental-Type Parasite Isolates

Marion Avril, Marianne Hathaway, Anand Srivastava, +5

PLoS ONE

Parasitic DiseaseMalariaImmunologyMolecular BiologyImmunodominance +15

Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy: A birth cohort study in Benin

Célia Dechavanne, Sébastien Dechavanne, Ibrahim Sadissou, +9

PLoS Medicine