Zhefu Que

Severe deficiency of the voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice

Jingliang Zhang, Xiaoling Chen, Muriel Eaton et al. · Cell Reports · 2021 · 116 citations · Full text

Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic Variant

Zhefu Que, Maria I. Olivero-Acosta, Jingliang Zhang et al. · Journal of Neuroscience · 2021 · 47 citations · Full text

Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids

Jiaxiang Wu, Jingliang Zhang, Xiaoling Chen et al. · Molecular Psychiatry · 2024 · 47 citations

Synaptic Plasticity, Developmental Biology, Autism-associated Scn2a-deficient Mice +9

Generation and basic characterization of a gene‐trap knockout mouse model of <i>Scn2a</i> with a substantial reduction of voltage‐gated sodium channel Na_v1.2 expression

Muriel Eaton, Jingliang Zhang, Zhixiong Ma et al. · Genes Brain & Behavior · 2020 · 38 citations · Full text

Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythms

Zhixiong Ma, Muriel Eaton, Yushuang Liu et al. · Neurobiology of Disease · 2022 · 32 citations · Full text