Leo B. Dungan

Co-administration With the Pharmacological Chaperone AT1001 Increases Recombinant Human α-Galactosidase A Tissue Uptake and Improves Substrate Reduction in Fabry Mice

Elfrida R. Benjamin, Richie Khanna, Adriane Schilling et al. · Molecular Therapy · 2012 · 93 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model

Nicole K. Polinski, Terina N. Martinez, A. Gorodinsky et al. · PLoS ONE · 2021 · 41 citations · Full text

Life Sciences, Genetics, Neurology +17

Glucosylceramide and Glucosylsphingosine Quantitation by Liquid Chromatography-Tandem Mass Spectrometry to Enable In Vivo Preclinical Studies of Neuronopathic Gaucher Disease

Rick Hamler, Nastry Brignol, Sean W. Clark et al. · Analytical Chemistry · 2017 · 29 citations

Life Sciences, Biochemistry, Neuroscience +17

In Vitro Inhibition of Midgut Microsomal P450s from Spodoptera eridania Caterpillars by Demethylation Inhibitor Fungicides and Plant Growth Regulators

L. B. Brattsten, Denis Berger, Leo B. Dungan · Pesticide Biochemistry and Physiology · 1994 · 25 citations

Life Sciences, Entomology, Insect Physiology +15

Migalastat Tissue Distribution: Extrapolation From Mice to Humans Using Pharmacokinetic Modeling and Comparison With Agalsidase Beta Tissue Distribution in Mice

Yi Shuan Shirley Wu, Richie Khanna, Virginia D. Schmith et al. · Clinical Pharmacology in Drug Development · 2021 · 11 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +11