Radosveta Gencheva

The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1

Dorian M. Cheff, Chuying Huang, Karoline Scholzen et al. · Redox Biology · 2023 · 245 citations · Full text

Life Sciences, Biochemistry, Pharmacology +12

Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin

Pierre Sabatier, Christian M. Beusch, Radosveta Gencheva et al. · Redox Biology · 2021 · 55 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus

Francesca Fata, Radosveta Gencheva, Qing Cheng et al. · Redox Biology · 2022 · 21 citations · Full text

Life Sciences, Biochemistry, Infectious Diseases +17

Elevated expression of miR-494-3p is associated with resistance to osimertinib in EGFR T790M-positive non-small cell lung cancer

Dominika Kaźmierczak, Inger Johanne Zwicky Eide, Radosveta Gencheva et al. · Translational Lung Cancer Research · 2022 · 20 citations · Full text

Medicine, Molecular Biology, Oncology +17

Efficient selenocysteine-dependent reduction of toxoflavin by mammalian thioredoxin reductase

Radosveta Gencheva, Qing Cheng, Elias S.J. Arnér · Biochimica et Biophysica Acta (BBA) - General Subjects · 2018 · 19 citations

Life Sciences, Biochemistry, Molecular Biology +11