Target Intestinal Microbiota to Alleviate Disease Progression in Amyotrophic Lateral Sclerosis

Yong-guo Zhang, Shaoping Wu, Jianxun Yi, +4

Clinical Therapeutics

Amyotrophic Lateral SclerosisDysbiosisHost-microbe InteractionsMicrobiotaImmunology +9

Leaky intestine and impaired microbiome in an amyotrophic lateral sclerosis mouse model

Shaoping Wu, Jianxun Yi, Yong-guo Zhang, +2

Physiological Reports

Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury

Ken Chen, Zaicheng Xu, Yukai Liu, +16

Science Translational Medicine

InflammationRedox SignalingIrisin ProtectsIschemia/reperfusion InjuryMitochondrial Function +10

β-aminoisobutyric Acid, l-BAIBA, Is a Muscle-Derived Osteocyte Survival Factor

Yukiko Kitase, Julian Vallejo, William G. Gutheil, +6

Cell Reports

β-Aminoisobutyric AcidMrgprd ExpressionDrinking WaterBiochemistryMedicine +12

Hyperactive Intracellular Calcium Signaling Associated with Localized Mitochondrial Defects in Skeletal Muscle of an Animal Model of Amyotrophic Lateral Sclerosis

Jingsong Zhou, Jianxun Yi, Ronggen Fu, +3

Journal of Biological Chemistry

Tight junction CLDN2 gene is a direct target of the vitamin D receptor

Yong-guo Zhang, Shaoping Wu, Rong Lu, +6

Scientific Reports

Irisin Protects Heart Against Ischemia-Reperfusion Injury Through a SOD2-Dependent Mitochondria Mechanism

Zhen Wang, Ken Chen, Yu Han, +13

Journal of Cardiovascular Pharmacology

Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals

Huaqiang Fang, Min Chen, Yi Ding, +21

Cell Research

Mitochondrial FunctionBiochemistrySuperoxide FlashPhysiologyCellular Physiology +8

Defective Mitochondrial Dynamics Is an Early Event in Skeletal Muscle of an Amyotrophic Lateral Sclerosis Mouse Model

Luo Guo, Jianxun Yi, Changling Ma, +4

PLoS ONE

Activation of Protein Kinase A Modulates Trafficking of the Human Cardiac Sodium Channel in <i>Xenopus</i> Oocytes

Jingsong Zhou, Jianxun Yi, NingNing Hu, +2

Circulation Research