Laura L. Kiefer

Hydrogen bond network in the metal binding site of carbonic anhydrase enhances zinc affinity and catalytic efficiency

Laura L. Kiefer, Steven A. Paterno, Carol A. Fierke · Journal of the American Chemical Society · 1995 · 177 citations

Engineering, Chemical Analysis, Hydrogen Bond Network +19

Functional Characterization of Human Carbonic Anhydrase II Variants with Altered Zinc Binding Sites

Laura L. Kiefer, Carol A. Fierke · Biochemistry · 1994 · 118 citations

Agouti structure and function: characterization of a potent .alpha.-melanocyte stimulating hormone receptor antagonist

Derril H. Willard, Wanda M. Bodnar, Cole O. Harris et al. · Biochemistry · 1995 · 107 citations

Protein Secretion, Amino Acid Protein, Molecular Biology +20

Reversal of the Hydrogen Bond to Zinc Ligand Histidine-119 Dramatically Diminishes Catalysis and Enhances Metal Equilibration Kinetics in Carbonic Anhydrase II

Chih-chin Huang, Charles A. Lesburg, Laura L. Kiefer et al. · Biochemistry · 1996 · 96 citations

Agouti regulation of intracellular calcium: role of melanocortin receptors

J. H. Kim, Laura L. Kiefer, Richard P. Woychik et al. · American Journal of Physiology-Endocrinology and Metabolism · 1997 · 82 citations

Cytoskeleton, Cellular Physiology, Insulin Signaling +20