Kokichi Honda

A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel

Katsunobu Hagihara, Miho Kazui, Atsushi Kurihara et al. · Drug Metabolism and Disposition · 2009 · 122 citations

Medicine, Biochemistry, Pharmacology +16

Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites

Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe et al. · Drug Metabolism and Disposition · 2011 · 36 citations

Pharmacy, Pharmacology, Toxicology +14

Raludotatug Deruxtecan, a CDH6-Targeting Antibody–Drug Conjugate with a DNA Topoisomerase I Inhibitor DXd, Is Efficacious in Human Ovarian and Kidney Cancer Models

Hirokazu Suzuki, Shotaro Nagase, C. Saito et al. · Molecular Cancer Therapeutics · 2024 · 32 citations · Full text

Medicine, Oncology, Pharmacology +17