Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF

San Pun, Alexandre Ferrão Santos, Smita Saxena, +2

Nature Neuroscience

Synaptic PlasticityNeuroanatomyMotoneuron DiseaseNeurological FunctionSelective Vulnerability +5

A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice

Smita Saxena, Erik Cabuy, Pico Caroni

Nature Neuroscience

Neurodegenerative DiseasesMolecular NeuroscienceNeurobiology Of DiseaseFals MiceDegenerative Disease +10

Neuroprotection through Excitability and mTOR Required in ALS Motoneurons to Delay Disease and Extend Survival

Smita Saxena, Francesco Roselli, Katyayani Singh, +4

Neuron

Neurodegenerative DiseasesAmyotrophic Lateral SclerosisNeurophysiologyNeurological FunctionDelay Disease +9

The Small GTPase Rab7 Controls the Endosomal Trafficking and Neuritogenic Signaling of the Nerve Growth Factor Receptor TrkA

Smita Saxena, Cecilia Bucci, Joachim Weis, +1

Journal of Neuroscience

Signal TransductionDevelopmental BiologyNeuritogenic SignalingG Protein-coupled ReceptorEndosomal Gtpase Rab7 +13

C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress

Niran Maharjan, Christina Künzli, Kilian Buthey, +1

Molecular Neurobiology

Hypersensitizing CellsReductive StressStressNatural SciencesMolecular Biology +6

Cloning of novel human SEC14p-like proteins: ligand binding and functional properties

Petra Kempná, Jean‐Marc Zingg, Roberta Ricciarelli, +3

Free Radical Biology and Medicine

Protein SecretionFunctional PropertiesSignal TransductionProtein FunctionProtein Assembly +8

Slow Waves Promote Sleep-Dependent Plasticity and Functional Recovery after Stroke

Laura Facchin, Cornelia Schöne, Armand Mensen, +6

Journal of Neuroscience

Mitochondrial impairments contribute to Spinocerebellar ataxia type 1 progression and can be ameliorated by the mitochondria-targeted antioxidant MitoQ

David Stucki, Céline Ruegsegger, Silvio Steiner, +4

Free Radical Biology and Medicine

MitophagyMitochondrial TransplantationMitochondrial FunctionMitochondrial ImpairmentsMitochondrial Dynamic +7

Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking

Smita Saxena, Charles L. Howe, José Miguel Cosgaya, +5

Molecular and Cellular Neuroscience

Late EndosomesTrka TraffickingMolecular PhysiologySignal TransductionDifferential Endocytic Sorting +11

Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology

Céline Ruegsegger, David Stucki, Silvio Steiner, +6

Neuron

Impaired Mtorc1-dependent ExpressionSignal TransductionSignaling PathwaySclerostinPhysiology +4