Kevin C. Johnson

Glioma progression is shaped by genetic evolution and microenvironment interactions

Frederick S. Varn, Kevin C. Johnson, Jason T. Huse et al. · Cell · 2022 · 498 citations · Full text

Medicine, Cancer Biology, Oncology +16

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-<i>N</i>2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-<i>N</i>4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Thomas H. Marsilje, Wei Pei, Bei Chen et al. · Journal of Medicinal Chemistry · 2013 · 412 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response

Kevin C. Johnson, Kevin Anderson, Elise T. Courtois et al. · Nature Genetics · 2021 · 267 citations · Full text

Life Sciences, Neuroscience, Oncology +17

Genome-wide DNA methylation profiles in progression to in situand invasive carcinoma of the breast with impact on gene transcription and prognosis

Thomas Fleischer, Arnoldo Frigessi, Kevin C. Johnson et al. · Genome biology · 2014 · 179 citations · Full text

Medicine, Molecular Biology, Oncology +17

Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer

Emre Kocakavuk, Kevin Anderson, Frederick S. Varn et al. · Nature Genetics · 2021 · 168 citations · Full text

Medicine, Cancer Biology, Oncology +7