Sören Swyter

Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals)

Matthias Schiedel, Daniel Herp, Sören Hammelmann et al. · Journal of Medicinal Chemistry · 2017 · 261 citations · Full text

Medicinal Chemistry, Biochemistry, Induced Degradation +15

Sirtuin 1 Inhibiting Thiocyanates (S1th)—A New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases

Nathalie Wössner, Zayan Alhalabi, Jessica González et al. · Frontiers in Oncology · 2020 · 35 citations · Full text

New chemical tools for probing activity and inhibition of the NAD ⁺ -dependent lysine deacylase sirtuin 2

Sören Swyter, Matthias Schiedel, Daria Monaldi et al. · Philosophical Transactions of the Royal Society B Biological Sciences · 2018 · 31 citations · Full text

Identification of Bichalcones as Sirtuin Inhibitors by Virtual Screening and In Vitro Testing

Berin Karaman, Zayan Alhalabi, Sören Swyter et al. · Molecules · 2018 · 27 citations · Full text

Three‐Component Aminoalkylations Yielding Dihydronaphthoxazine‐Based Sirtuin Inhibitors: Scaffold Modification and Exploration of Space for Polar Side‐Chains

Steffen Vojacek, Katja Beese, Zayan Alhalabi et al. · Archiv der Pharmazie · 2017 · 19 citations